Fentanyl Overdose Death Rate by State 2025
About This Dataset
Fentanyl Overdose Death Rate by State 2025How the data is collected. The counts come from provisional death certificate data that the National Center for Health Statistics (NCHS) at the CDC publishes every month, here for the 12 months ending December 2025. The drug category is ICD-10 code T40.4 on the death certificate. The rate is CDC's count divided by the BEA 2025 population estimate.
Background. Nationally 38,462 deaths involved synthetic opioids, 54.4 per cent of all overdose deaths. They fell 21.0 per cent from 2024, faster than overdose deaths overall.
Limits. Louisiana and Nevada are left out because CDC does not publish drug-specific counts for them in this dataset. A death involving several drugs is counted under each of them.
Alaska had the second-highest fentanyl death rate, 29.4, and the highest rate for methamphetamine and other stimulants.
Key Findings
Fentanyl Overdose Death Rate by State 2025
Data Insights
Numbers, trends & sources behind this chart
Methodology & source
- Data source
- CDC National Center for Health Statistics, VSRR Provisional Drug Overdose Death Counts
- Coverage
- 49 entities · 2025 · 49 observations
- Measure
- Synthetic Opioid Deaths per 100,000 People
- Last updated
- 2 October 2026
- Compiled by
- The ANYSTAT team, from the source above
- Values are shown as reported by the source. Nothing is rescaled, rebased or converted — the only changes are thousand separators and decimals shown to two places.
- Entities are ranked highest-first on their value in 2025.
An article using this data
Rankings & Full Data
49 records · Synthetic Opioid Deaths per 100,000 People · ranked by 2025
Data Sources & References
All external sources cited in this dataset
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